# Warding Rune of Annihilation
**Category:** Warding
**Tier:** Normal
Warding Rune of Annihilation
Warding Rune of Annihilation — rune in Path of Exile 2.
Source: game_clientExtracted: 6/20/2026
Warding Rune of Annihilation — rune in Path of Exile 2.